RNAi: A Recent Revolutionary Tool for Understanding of Basic Biology.
- Author:
Dong Kil JUNG
1
;
Young Suk CHO
;
Won Kil LEE
Author Information
1. Department of Laboratory Medicine, Hongseong Medical Center, Korea.
- Publication Type:Review
- Keywords:
RNAi;
Gene-silencing;
Gene function;
Therapeutic potential
- MeSH:
Biology*;
Insects;
RNA;
RNA Interference;
RNA, Double-Stranded
- From:Korean Journal of Clinical Microbiology
2007;10(1):1-5
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
RNA interference (RNAi) is a gene-silencing technology by which small double-stranded RNAs are used to target the degradation of RNA with complementary sequence. RNAi is found in a wide variety of organisms (Caenorhabditis elegans, insects, plants, microorganisms and animals). With RNAi, we have harnessed the gene function to be explored, revolutionized our ability to perform large-scale genetic screens, and even therapeutic potential.
