Clinical Features in Korean Patients with Sarcoid Uveitis.
10.3341/jkos.2008.49.9.1483
- Author:
Tae Wan KIM
1
;
Hum CHUNG
;
Hyeong Gon YU
Author Information
1. Department of Ophthalmology, Seoul Metropolitan Boramae Hospital, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Immunosuppressive agents;
Korean;
Sarcoid uveitis;
Steroid
- MeSH:
Adrenal Cortex Hormones;
Humans;
Immunosuppressive Agents;
Inflammation;
Medical Records;
Recurrence;
Sarcoidosis;
Steroids;
Uveitis;
Uveitis, Anterior
- From:Journal of the Korean Ophthalmological Society
2008;49(9):1483-1490
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate the clinical features of Korean patients with sarcoid uveitis. METHODS: The medical records of patients with endogenous uveitis who were recruited from the uveitis clinic at Seoul National University Hospital were reviewed. Sex, age at presentation, ocular symptoms and signs, treatment, complications, and the rate of recurrence were analyzed. RESULTS: Of 440 patients with endogenous uveitis, 31 (7.1%) with sarcoidosis were included. The mean age at onset was 54.5 years. Sarcoidosis patients with uveitis tended to be older than those without uveitis (44.1 years). Uveitis was the primary manifestation of sarcoidosis in 16 of 31 patients (51.6%). Anterior uveitis was the most common in terms of the anatomic location of inflammation (54.8%), and posterior involvement (38.7%) was not rare. Systemic corticosteroid therapy was administered to 28 patients (90.3%). Five patients (16.1%) received corticosteroids combined with immunosuppressive agents. CONCLUSIONS: Sarcoid uveitis is not a rare etiology of endogenous uveitis. Topical or systemic corticosteroids could control inflammation in most cases, but immunosuppressive agents are needed in a small percentage of patients. Steroids combined with immunosuppressive agents can prevent severe visual losses in such patients.
