A Case of Cytophagic Histiocytic Panniculitis Associated with Hemophagocytic Lymphohistiocytosis
- Author:
Hyun Ji LEE
1
;
Ji Yeon HAM
;
Kyung Duck PARK
Author Information
1. Department of Dermatology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Korea
- Publication Type:Case Report
- From:Korean Journal of Dermatology
2021;59(2):157-159
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cytophagic histiocytic panniculitis (CHP) is a rare form of panniculitis, presenting lymphohistiocytic infiltration within subcutaneous fat tissue with phagocytic histiocytes. Associated systemic symptoms includes fever, hepatosplenomegaly, lymphadenopathy, serositis, pancytopenia, hepatic abnormalities, hypertriglyceridemia, and coagulopathy, which are the features of hemophagocytic lymphohistiocytosis (HLH). The patients of CHP associated with HLH may have nonfatal acute/intermittent, or rapidly fatal clinical courses, so the prompt and accurate diagnosis with immunosuppressive treatments are significant.
