Low Doses of Baclofen Induced Nonconvulsive Status Epilepticus in a Patient with Chronic Kidney Disease
- Author:
Soo-Hyun KIM
1
;
Sumin KIM
;
Hyunji KIM
;
Hyung Ho KIM
;
Ji Young YUN
;
Jung Hwa LEE
;
Geon Ha KIM
Author Information
- Publication Type:증례
- From:Journal of the Korean Neurological Association 2021;39(1):26-29
- CountryRepublic of Korea
- Language:Korean
- Abstract: Baclofen, a gamma-aminobutyric acid B agonist, is frequently used in the treatment of various neurologic diseases including spasticity, dystonia and trigeminal neuralgia. This drug usually acts at the presynaptic motor neuron to induce an antispastic response. Oral baclofen toxicity is extremely rare, but is often reported to affect patients with renal disease. Here, we report a patient with chronic kidney disease who was treated with relatively low doses of baclofen (5 mg twice per day) and experienced nonconvulsive status epilepticus.
