Toremifene-associated endometrial polyp: A case report and review of the literature.
- Author:
Eun Hee PARK
1
;
Sung Yun BAHNG
;
Tae Sung KIM
;
Seong Taek MUN
;
Jib Kwang CHUNG
;
Seok Min LEE
;
So Young JIN
Author Information
1. Department of Obstetrics and Gynecology, Soonchunhyang University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Toremifene;
endometrial polyp
- MeSH:
Animals;
Breast Neoplasms;
Estrogen Receptor Modulators;
Female;
Gastrointestinal Neoplasms;
Humans;
Mice;
Polyps*;
Tamoxifen;
Toremifene
- From:Korean Journal of Obstetrics and Gynecology
2002;45(7):1214-1217
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Antiestrogens have been widely used in the treatment of breast cancer patients. Although tamoxifen is one of the most prevalent antiestrogens, some reported its hepatocarcinogenic effects and the long-term treatment may increase the risk of endometrial and gastrointestinal cancer. Toremifene is an interesting new antiestrogen and have a similar antitumor efficacy as tamoxifen, with less side-effect including less uterotrophic effect compared to tamoxifen, in mice. we report a case of endometrial polyp which were associated with toremifene use, in postmenopausal woman with breast cancer, with a brief review of literature.
