Dysgeusia as Anti-GQ1b Antibody Syndrome with Brainstem Involvement: A Tractography Case Report
10.34160/jkds.2021.11.1.010
- Author:
Yeonjae HAN
1
;
Young Kook KIM
;
Geun-Young PARK
;
Sang Ah JEONG
;
Sun IM
Author Information
1. Departments of Rehabilitation Medicine, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea
- Publication Type:Case Report
- From:
Journal of the Korean Dysphagia Society
2021;11(1):72-77
- CountryRepublic of Korea
- Language:English
-
Abstract:
Dysgeusia and dysphagia are rarely reported as the sole clinical symptoms of anti-GQ1b antibody syndrome involving the cranial nerves (CN). According to previous reports, those exhibiting bilateral facial nerve palsy or ophthalmoplegia or both are followed by bulbar dysfunctions (CNs IX and X). This paper reports a case of a 22-year-old man showing dysgeusia with dysphagia and mild limb weakness. Fiberoptic endoscopy revealed signs of residues after swallowing. The nerve conduction study (NCS) in the limbs and conventional brain magnetic resonance imaging were normal. Further workup revealed a positive serum anti-GQ1b antibody. The diffusion tension weighted brain images with tractography revealed involvement to the bilateral corticobulbar and corticospinal tract at the brainstem level. Although his normal NCS and conventional brain MRI made the diagnosis difficult, it was confirmed to be a rare variant of anti-GQ1b antibody syndrome showing corticobulbar and corticospinal tract involvement. The patient showed excellent recovery after dysphagia treatment.
