Associations of serum 25(OH)D levels with depression and depressed condition in Korean adults: results from KNHANES 2008-2010.
10.4163/jnh.2014.47.2.113
- Author:
Sle KOO
1
;
Kyong PARK
Author Information
1. Department of Food & Nutrition, Yeungnam University, Gyeongsan, Gyeongbuk 712-749, Korea. kypark@ynu.ac.kr
- Publication Type:Original Article
- Keywords:
depression;
depressed condition;
25-hydroxyvitamin D;
Korean adults
- MeSH:
Adult*;
Brain;
Central Nervous System;
Cross-Sectional Studies;
Depression*;
Diagnosis;
Epidemiologic Studies;
Female;
Human Body;
Humans;
Life Style;
Logistic Models;
Male;
Mental Health;
Nutrition Surveys;
Prevalence;
Vitamin D;
Vitamin D Deficiency
- From:Journal of Nutrition and Health
2014;47(2):113-123
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Vitamin D has been known to play an important role in the central nervous system and brain functions in the human body, and cumulative evidence has shown that vitamin D deficiency might be linked with various mental health conditions. Epidemiologic studies have shown that vitamin D deficiency may be associated with higher risk of depression in the US and European populations. However, limited information is available regarding the association between vitamin D status and depression in the Korean population. The objective of this study was to examine the associations between vitamin D levels and prevalence of depression. METHODS: We conducted a cross-sectional analysis using nationally representative data from the 2008-2010 Korean National Health and Nutrition Examination Survey from which serum 25-hydroxyvitamin D concentrations were available. A total of 18,735 adults who had available demographic, dietary, and lifestyle information were included in our analysis. We defined "depression" with a diagnosis by a physician. "Depressed condition" was defined as having feelings of sadness or depression without diagnosis by a physician. RESULTS: The prevalence of depression was 1.63% and 5.43% in Korean men and women, respectively; 12.5% of men and 26.1% of women were defined as the group having depressed conditions. In multivariate logistic regression models, no significant associations were observed between vitamin D status and prevalence of depression or depressed conditions in Korean men and women. CONCLUSION: We found no association between vitamin D insufficiency and depression/depressed conditions in Korean adults. Future large prospective studies and randomized controlled trials are needed to confirm this relationship.
