Current Status of COVID-19 Vaccine Development: Focusing on Antigen Design and Clinical Trials on Later Stages
- Author:
Pureum LEE
1
;
Chang-Ung KIM
;
Sang Hawn SEO
;
Doo-Jin KIM
Author Information
- Publication Type:Review Article
- From:Immune Network 2021;21(1):e4-
- CountryRepublic of Korea
- Language:English
- Abstract: The global outbreak of coronavirus disease 2019 (COVID-19) is still threatening human health, economy, and social life worldwide. As a counteraction for this devastating disease, a number of vaccines are being developed with unprecedented speed combined with new technologies. As COVID-19 vaccines are being developed in the absence of a licensed human coronavirus vaccine, there remain further questions regarding the long-term efficacy and safety of the vaccines, as well as immunological mechanisms in depth. This review article discusses the current status of COVID-19 vaccine development, mainly focusing on antigen design, clinical trials in later stages, and immunological considerations for further study.
