A Case of Herpes Zoster Granulomatous Dermatitis:Report of Wolf’s Isotopic Response
- Author:
Ji ha YOON
1
;
Ye ji JANG
;
Eun joo PARK
;
Kwang joong KIM
;
Kwang ho KIM
Author Information
- Publication Type:CASE REPORT
- From:Annals of Dermatology 2021;33(2):186-189
- CountryRepublic of Korea
- Language:English
- Abstract: Wolf’s isotopic response refers to the occurrence of a novel skin disease at the site of a preceding treated or untreated skin disease. Although the most common preceding skin disease was found to be herpes zoster (HZ), HZ-related dermatological phenomena are not well known in the literature. We report a case of HZ granulomatous dermatitis in a 77-year-old female with a previous history of hypertension, diabetes mellitus, chronic kidney disease, and HZ. She presented with a 3-month history of a pruritic skin lesion on her right thigh. The location of the lesion was consistent with a previous HZ site. Histopathological examination revealed lympho-histiocytic infiltration in the superficial dermis, forming a granulomatous structure. Based on clinical and histopathological findings, we made a diagnosis of granulomatous dermatitis at a previous HZ site. We assumed that the lesion arose from an isotopic response of Wolf. The patient was treated with topical steroids for 3 months and showed clearance of the lesion and symptom. We suggest that treatment should be based on the individual disease, which in our case was topical steroid.
