Association of Benign Prostate Hyperplasia with Male Pattern Baldness.
- Author:
Bong Ryoul OH
1
;
Seong Jin KIM
;
Jai Dong MOON
;
Hyeung Nam KIM
;
Dong Deuk KWON
;
Young Ho WON
;
Soo Bang RYU
;
Yang Il PARK
Author Information
1. Department of Urology, Chonnam University Medical School, Kwangju, Korea.
- Publication Type:Original Article
- Keywords:
Benign prostate hyperplasia;
Baldness
- MeSH:
Alopecia*;
Humans;
Hyperplasia*;
Male*;
Prostate*
- From:Korean Journal of Urology
1998;39(6):563-567
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Both benign prostate hyperplasia(BPH) and male pattern baldness (androgenic alopecia) share the pathogenesis of androgen dependent disorder in addition to afflict large population of old men with chronobiological progress. However, it is unclear that both diseases relate to each other on epidemiologic basis. We evaluated the frequency and severity of male pattern baldness between the patients with BPH and control group. MATERIALS AND METHODS: A total of 225 patients with BPH(mean age: 69.3+/-6.5years) and 160 controls(mean age: 68.5+/-6.4 years), whose age over 60, was included in this study. The estimation of bladness severity was based on the Norwood's classification(grade 1 to VII). International prostate symptom score (IPSS) and genetic tendency of baldness were also evaluated. The difference of IPSS and grade of baldness between two groups were analysed by Mann-whitney test and the frequency of inherited baldness were compared by Chisquare test. Correlations between severity of baldness and IPSS of each group were estimated by Spearman's rank correlation method. RESULTS: It was noted that the patients with BPH had an apparent higher grade of male pattern baldness in comparison with that of controls(median value of IV to 111, p<0.001). The proportion of male pattern baldness with grade IV or greater in BPH group was significantly larger than that of controls(53.8% versus 36.9%, p<0.01). There was greater frequency of inheritant baldness in BPH group than in controls(31.6% versus 12.5%, p<0.001). No significant correlations were noted between baldness severity and IPSS in both groups. CONCLUSIONS: Our study demonstrated there was a strong association of BPH with male pattern baldness.
