Multi-disciplinary team of the treatment of bilateral lung transplantation for pediatric cystic fibrosis
10.3969/j.issn.1674-7445.2021.02.008
- VernacularTitle:双肺移植治疗儿童囊性纤维化的多学科综合诊疗
- Author:
Shengfei WANG
1
;
Jingyu CHEN
;
Yi LIU
;
Mingfeng ZHENG
;
Wenjun MAO
Author Information
1. Department of Thoracic Surgery, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214023, China
- Publication Type:Research Article
- Keywords:
Bilateral lung transplantation;
Multi-disciplinary team (MDT);
Pediatric lung transplantation;
Cystic fibrosis;
Cystic fibrosis transmembrane conductance regulator (CFTR);
Type Ⅰ respiratory failure;
Extracorporeal membrane oxygenation (ECMO);
Lung allocation score (LAS)
- From:
Organ Transplantation
2021;12(2):184-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the surgical efficacy of bilateral lung transplantation for pediatric cystic fibrosis through multi-disciplinary team (MDT). Methods Preoperative MDT consultation was delivered for a 10-year-old child with rare end-stage cystic fibrosis to establish the corresponding treatment protocol. Results The child was diagnosed with cystic fibrosis for 5 years, and the indication of lung transplantation were confirmed. After preoperative MDT consultation, bilateral lung transplantation via a Clam-shell incision was determined. The vital signs were maintained stable during operation. Postoperatively, ventilator-assisted ventilation, anti-infection, immunosuppression, acid suppression, prevention of stress ulceration and other treatments were delivered. Individualized treatment was given according to the characteristics of the child, and the child was well recovered. Conclusions Through preoperative MDT consultation, lung transplantation yields satisfactory surgical efficacy in treating pediatric cystic fibrosis and lowers the risk of postoperative complications, which deserves application in clinical practice.
