Clinical value of sST2 in replacement of NT-proBNP in cardiac function evaluation in renal failure patients after cardiac surgery
- VernacularTitle:sST2 替代 NT-proBNP 评价心脏术后肾功能不全患者心功能的临床价值
- Author:
Dong ZHAO
1
;
Bo WU
2
;
Jinqiang SHEN
1
;
Chunsheng WANG
1
Author Information
1. Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R.China
2. Department of Cardiology, Yangpu Hospital, Tongji University, Shanghai, 200082, P.R.China
- Publication Type:Journal Article
- Keywords:
Soluble suppression of tumorigenesis-2 (sST2);
N-terminal fragment of the brain natriuretic peptide precursor (NT-proBNP);
cardiac function index;
perioperative period;
surgery
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2021;28(03):331-334
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of soluble suppression of tumorigenesis-2 (sST2) in replacement of N-terminal fragment of the brain natriuretic peptide precursor (NT-proBNP) in cardiac function evaluation in renal failure patients after cardiac surgery. Methods Sixty patients with renal insufficiency after cardiac surgery from January 2019 to June 2019 were divided into a test group, including 34 males and 26 females, with an average age of 49-78 (63.3±4.5) years. Another 60 patients with normal renal function were divided into a control group, including 37 males and 23 females, with an average age of 53-77 (61.7±3.8) years. The perioperative left ventricular ejection fraction, cardiac troponin T, creatine kinase-MB, sST2 and NT-proBNP were compared. Results In patients of the test group, the NT-proBNP level increased significantly during perioperative period, and the change range was different from other cardiac function indexes. The change of sST2 in perioperative period was similar to other cardiac function indexes, which could reflect the change degree of cardiac function after operation. Conclusion sST2 is more important to reflect the change degree of cardiac function in patients with renal dysfunction after cardiac surgery than NT-proBNP.
