Advances in research on pediatric oral liquid dosage forms
10.11665/j.issn.1000-5048.20210116
- VernacularTitle:儿童口服给药液体剂型研究进展
- Author:
Yue MENG
1
;
Ziqiang ZHANG
;
Shuwang HE
;
Jing YAO
Author Information
1. 中国药科大学药学院
- Publication Type:Journal Article
- Keywords:
pediatric medicines;
oral liquid dosage forms;
taste masking technology;
safe excipients;
progress
- From:
Journal of China Pharmaceutical University
2021;52(1):113-121
- CountryChina
- Language:Chinese
-
Abstract:
Liquid preparations are the commonly used oral dosage forms in pediatric clinical practice.This review introduces the pediatric oral liquid dosage forms including extemporaneous preparation of oral liquid formulations, oral liquid sustained and controlled release formulations, nanosuspensions, nanoemulsions, self-nanoemulsions and milk-based liquid formulations.In addition, the efficient flavoring and taste masking technologies, using safe pharmaceutical excipients, high-demanding technical standards and verification strategies, establishing excellent workflow management systems can contribute to the development and application of pediatric oral liquid dosage forms which are safer, more effective and better compliant.This review is helpful in laying the relevant theoretical foundation for further studies on pediatric oral liquid dosage forms.
