Association between Toll-like receptor 4 and pancreatic cancer
DOI:10.3969/j.issn.1001-5256.2021.02.050
- VernacularTitle:Toll样受体4与胰腺癌的关系
- Author:
Chenglong CHU
1
;
Chaohui TANG
;
Luyao XU
;
Changxu LI
;
Yingchao WANG
Author Information
1. Department of Hepatobiliary Surgery, The First Hospital of Jilin University, Changchun 130021, China
- Publication Type:Research Article
- Keywords:
Pancreatic Neoplasms;
Toll-Like Receptor 4;
Therapeutics
- From:
Journal of Clinical Hepatology
2021;37(2):485-488
- CountryChina
- Language:Chinese
-
Abstract:
Toll-like receptor 4 (TLR4) is a key regulator of innate and adaptive immune response. The role of TLR4 in pancreatic diseases is a research hotspot in recent years, and a large number of studies have shown that TLR4 is closely associated with pancreatic cancer. This article mainly discusses the abnormal expression and regulation mechanism of TLR4 in pancreatic cancer and its potential in cancer treatment, so as to provide new ideas for the pathogenesis and treatment of pancreatic cancer.