Clinical Efficacy of Modified Sanzi Yangqintang and Colon Hydrotherapy on Treatment of Non-alcoholic Fatty Liver Disease with Phlegm-dampness
10.13422/j.cnki.syfjx.20200326
- VernacularTitle:三子养亲汤加味结肠水疗治疗痰湿内阻型非酒精性脂肪性肝病的临床疗效
- Author:
Kai-ping JIANG
1
;
Kai-zhou HUANG
1
;
Jian-hong LI
1
;
Teng-yu QIU
1
;
Xiao-ai MO
1
;
Hong-tao HU
1
;
Wen-qiang GUO
1
;
Jian REN
1
;
Lei ZHANG
1
;
Qing-hua HUANG
1
;
Ying ZUO
1
;
Hai-jun CUI
1
;
Xu-li CHEN
1
Author Information
1. Foshan Hospital of Traditional Chinese Medicine, Foshan 528000, China
- Publication Type:Research Article
- Keywords:
modified Sanzi Yangqintang;
Chinese medicine colon hydrotherapy;
non-alcoholic fatty liver disease;
phlegm-dampness
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2020;26(3):31-36
- CountryChina
- Language:Chinese
-
Abstract:
Objective::To explore the clinical efficacy of modified Sanzi Yangqintang combined with colon hydrotherapy in the treatment of non-alcoholic fatty liver disease (NAFLD) with phlegm-dampness. Method::Totally 100 patients with NAFLD were selected and randomly divided into treatment group (50 cases) and control group (50 cases). Both groups were orally given silybin and glycyrrhizic acid diamine capsules.The treatment group was also added with modified Sanzi Yangqintang and colon hydrotherapy.The treatment lasted for 7 days.The control group was also added with saline colon hydrotherapy.Main traditional Chinese medicine (TCM) syndrome scores and liver function indexes before and after treatment [alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamate transpeptidase (GGT)], blood lipid routine [cholesterol (TCH), triglyceride (TG)], inflammatory factors [interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α)], FibroScan measurement [liver stiffness measurement (LSM), controlled attenuation parameters (CAP)], uric acid and body weight changes were observed.Adverse reactions were observed, and the patient's medication safety was evaluated. Result::TCM syndrome score, liver enzyme index, blood lipid index, inflammatory factor index, FibroScan CAP, uric acid and body weight of the two groups were significantly reduced than those before treatment(P<0.05, P<0.01) .There was no significant difference in liver enzymes, TCH, IL-6 and LSM between treatment group and control group.And TCM syndrome scores, UA, TNF-α, FibroScan CAP decreased were significantly different from control group (P<0.05). Conclusion::Modified Sanzi Yangqintang combined with colon hydrotherapy can not only alleviate NAFLD with phlegm-dampness symptoms, but also significantly reduce triglyceride, tumor necrosis factor and FibroScan CAP and body mass, with certain clinical efficacy in a short term.
