Advances in Research on Different Compatibility Ratios of Coptidis Rhizoma-Evodia Fructus
10.13422/j.cnki.syfjx.20200213
- VernacularTitle:不同配伍比例的黄连-吴茱萸药对研究进展
- Author:
Xu WANG
1
;
Bei-lei XU
1
;
Di WU
1
;
Na-na YANG
1
;
Wen-lan LI
1
;
Shu-sen LIU
1
;
Wen-bin SUN
1
;
Yang HU
1
;
Ya TU
2
;
Cai-dan REZENG
3
Author Information
1. School of Pharmacy, Harbin University of Commerce, Harbin 150076, China
2. Chinese Medicine Development Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China
3. School of Pharmacy, Qinghai Nationalities University, Xining 810007, China
- Publication Type:Research Article
- Keywords:
Coptidis Rhizoma-Evodia Fructus;
herb pair;
chemical constituents;
pharmacological action
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2020;26(3):21-30
- CountryChina
- Language:Chinese
-
Abstract:
Coptidis Rhizoma-Evodia Fructus is a classic herb pair in traditional Chinese medicine prescriptions, the famous prescription is called Zuojinwan, which comes from Danxi Xinfa, is composed of Coptidis Rhizoma-Evodia Fructus (6∶1). In this formula, Coptidis Rhizoma has the effect of clearing heat and drying diuresis, purging fire to remove toxin and clearing heart. Evodia Fructus has the effects of expelling cold and alleviating pain, checking upward adverse flow of Qi tostop vomiting, and assisting yang to stop diarrhea. Coptidis Rhizoma has the properties of bitter and cold, and Evodia Fructus has the properties of pungent and calidus. Pungent drugs have divergent effects, and bitter drugs have sedimentation effect, when used in combination, they can clear the liver and purge fire, calm the adverse-rising energy and stop vomiting. On the basis of Zuojinwan, Coptidis Rhizoma-Evodia Fructus medicine has derived different compatibility ratios. Different ratios are different in terms of efficacy, usage, clinical application. Although with the application of modern analytical instruments and the development of molecular pharmacology theory, the chemical constituents and Pharmacological effects of Coptidis Rhizoma and Evodia Fructus have been fully studied, as to the principle of compatibility, and the study of pharmacological effects and chemical constituents after the compatibility of the two drugs in different proportions, there is still no comprehensive system summary. This article makes a systematic and comprehensive explanation of Coptidis Rhizoma-Evodia Fructus from the aspects of famous literature, chemical composition, pharmacological effects and clinical applicationthrough querying literature and ancient books. In order to make this herb pair more standardized, and provide reference materials for further research and development for this herb pair.
