Progress in Research on Effect of Processing on Chemical Constituents and Pharmacological Effect of Notoginseng Radix et Rhizoma
10.13422/j.cnki.syfjx.20201158
- VernacularTitle:炮制对三七化学成分及药理作用影响的研究进展
- Author:
Na XING
1
;
Dong-hui PENG
1
;
Zhi-hong ZHANG
2
;
Zi-dong ZHANG
1
;
Hai-xue KUANG
1
;
Qiu-hong WANG
1
Author Information
1. Key Laboratory of Basic and Applied Research of Northern Medicine,Ministry of Education,Heilongjiang Key Laboratory of Pharmacodynamic Material Basis of Traditional Chinese Medicine (TCM) and Natural Medicine,Heilongjiang University of Chinese Medicine,Harbin 150040,China
2. School of TCM,Guangdong Pharmaceutical University,Guangzhou 510006,China
- Publication Type:Research Article
- Keywords:
Notoginseng Radix et Rhizoma;
processing;
chemical constituent;
pharmacological action;
dispersing blood stasis and stopping bleeding;
invigorating Qi and blood
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2020;26(16):210-217
- CountryChina
- Language:Chinese
-
Abstract:
Notoginseng Radix et Rhizoma, one of precious and important traditional Chinese medicinal herb, has the functions of dispersing blood stasis and stopping bleeding, detaching swelling and alleviating pain, and invigorating Qi and blood. It is a traditional Chinese medicine for promoting blood circulation and removing blood stasis. After processing, the efficacy of Notoginseng Radix et Rhizoma was obviously different, the raw products mainly dispersed blood stasis and hemostasis, while the main effect of processed products was to replenish blood and Qi. In recent years, more attention has been paid to Notoginseng Radix et Rhizoma research, mainly focusing on the chemical constituent, pharmacological action and clinical application of the raw products. Although the research on processed Notoginseng Radix et Rhizoma has been increasing in these years, the mechanism of processing and the changes of bioactive constituents before and after processing are still unclear. This paper systematically summarized the modern processing methods of Notoginseng Radix et Rhizoma and compared the changes in chemical constituent and pharmacological action before and after processing through literature search. It is proposed that modern technologies should be put forward to study the correlation between the chemical constituent transformation and enriching blood as the breakthrough point, in order to explain the processing mechanism of Notoginseng Radix et Rhizoma, improve the quality evaluation system of this decoction pieces, and provide guarantee for the safety and effectiveness of its clinical medication.
