Application of linac-based fractionated stereotactic radiation therapy in treatment of oligo brain metastases
10.3760/cma.j.cn115355-20200401-00166
- VernacularTitle:基于直线加速器的分次立体定向放疗在脑寡转移肿瘤中的应用
- Author:
Chong ZHOU
1
;
Ruyuan GUO
;
Youyou XIA
;
Lian LIAN
;
Haitao YIN
Author Information
1. 江苏省徐州市中心医院放疗科 221009
- From:
Cancer Research and Clinic
2020;32(11):741-744
- CountryChina
- Language:Chinese
-
Abstract:
Brain metastases are common in oncologic patients. Stereotactic radiosurgery (SRS) is an effective treatment for oligo brain metastases. However, SRS is not suitable for large metastatic lesions. Fractionated stereotactic radiation therapy (FSRT) is a new option for the treatment of brain metastases. It can deliver high doses of radiation to tumor while protecting the normal tissues and organs outside the irradiation field as much as possible and maintaining good local control rate of tumors. This article reviews the dose-response relationship and adverse reactions of FSRT with different fractionated dose schemes, and the progress of FSRT combined with targeted therapy and immunotherapy.
