Precision treatment of colorectal cancer with rare gene mutations
10.3760/cma.j.cn115355-20200321-00128
- VernacularTitle:少见和罕见基因突变结直肠癌的精准治疗
- Author:
Zhiqin CHEN
1
;
Ming QUAN
;
Jingde CHEN
;
Yong GAO
Author Information
1. 同济大学附属东方医院肿瘤科，上海 200123
- From:
Cancer Research and Clinic
2020;32(10):669-672
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is the most common gastrointestinal malignant tumor. Advances of targeted therapy and immunotherapy have significantly improved the prognosis of patients with colorectal cancer. In recent years, with the concept of precision medicine, molecular classification of colorectal cancer based on molecular pathology has been widely accepted. Patients with BRAF, HER2, MET, PIK3CA, MEK, BRAC1, BRAC2 and other rare driver gene mutations have been gradually paid attention. This article reviews the treatment advances in colorectal cancer with rare driver gene mutations.
