Progress of relationship between vaginal microenvironment and local immunity and cervical cancer
10.3760/cma.j.cn115355-20200117-00025
- VernacularTitle:阴道微环境及局部免疫与子宫颈癌关系的研究进展
- Author:
Zilin YANG
1
;
Zhilian WANG
Author Information
1. 山西医科大学研究生院,太原 030001
- From:
Cancer Research and Clinic
2020;32(5):370-373
- CountryChina
- Language:Chinese
-
Abstract:
High-risk human papillomavirus (HR-HPV) infection is the main cause of cervical cancer. Current research shows that other factors work together with HPV to affect the occurrence and development of cervical cancer. Under normal circumstances, the vaginal microbiota can play a fundamental role in maintaining the balance of the vaginal microenvironment and anti-inflammatory and anti-tumor together with the host immune system. Once the body is infected with HPV in synergy with other factors, it will accelerate the progression of cervical cancer. This article reviews the changes in the vaginal microenvironment and local immune response of cervical cancer.