Cosmetic adverse reaction: a clinical analysis of 820 cases
10.3760/cma.j.issn.1671-0290.2020.05.019
- VernacularTitle:820例化妆品不良反应分析
- Author:
Jiayu SUN
1
;
Ziyu CHAI
;
Xiaoya YIN
;
Yanjie HAO
;
Weiyu WU
;
Yaqiong BAI
;
Han SUN
;
Rongxin ZHANG
;
Ling JIN
;
Xuezhu XU
Author Information
1. 大连医科大学附属第二医院皮肤科 116027；宁夏回族自治区人民医院皮肤科，银川 750021
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2020;26(5):424-427
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To provide epidemiological data and clinical evidence for cosmetic adverse reactions.Methods:A retrospective clinical analysis was carried out on a total 820 outpatients (23 males and 797 females) suspected to be with cosmetic adverse reactions from January 2014 - October 2017, and average age of these patients was 7~75 (32.66±8.09) years. Suspicious cosmetics patch tests were performed in some patients. Suspicious cosmetics patch tests were performed in 687 patients.Results:Among 820 patients with cosmetic adverse reactions, women accounted for 97.20% and men accounted for 2.80%. Age distribution was most common among young people aged 21-40 years, accounting for 71.34%. The highest level of education was higher education, accounting for 59.69%. Occupational distribution was most commonly concentrated in employees and unemployed persons, accounting for 28.54% and 18.66%, respectively. A history of cosmetics allergies accounted for 17.28%. Cosmetic contact dermatitis was the most common clinical type of cosmetic adverse reactions, accounting for 92.70%. A total of 1682 suspected pathogenic cosmetics were involved. The positive rate of the cosmetic original patch test was 42.39%. Among the cosmetics with a positive patch test, moisturizing, anti-wrinkle and whitening freckle cosmetics accounted for the highest proportion, 31.59%, 15.09%, and 12.68%, respectively.Conclusions:Cosmetic contact dermatitis is the most common type of cosmetic adverse reaction. Patch testing is helpful in identifying the contact allergens in cosmetic adverse reaction.
