Clinical effects of allogenic decalcified bone matrix as material for rebuilding midline structure in rhinoplasty
10.3760/cma.j.issn.1671-0290.2020.05.008
- VernacularTitle:脱钙骨基质作为鼻成形中线支架材料的临床效果
- Author:
Chen ZHANG
1
;
Liang CHEN
;
Chunying GE
;
Jieqing WANG
;
Wei YANG
Author Information
1. 大连大学附属新华医院整形外科 大连大学整形外科研究所 116021
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2020;26(5):385-388
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the possibility of allogenic decalcified bone matrix used as material to rebuild the midline structure in rhinoplasty.Methods:From January 2018 to June 2018, allogenic decalcified bone matrix was used as material to rebuild the midline structure in rhinoplasty in six carefully selected patients, who did not have enough septum and conchal cartilage to be harvested and refused to have costal cartilage harvested. Nasal length and tip projection were measured preoperatively, 2 weeks and 18 months postoperatively.Results:All patients were satisfied with the appearance of the nose two weeks after operation. However, four patients experienced the reduction of tip projection in 18 months postoperatively and needed revised rhinoplasty. In the revised operation, the implanted allogenic decalcified bone matrix could not be removed integrally. Matrix residues were harvested and observed under the microscope, which showed fragment of the matrix and fibers surrounded by inflammatory cells and foreign-body giant cells. No osteocyte was found in the ground substances of bone.Conclusion:The commercial allogenic decalcified bone matrix applied in this study is not recommended to use as the material for rebuilding the midline structure in rhinoplasty.