Botulinum toxin type A injections in the facial plastic surgery incision: a meta-analysis
10.3760/cma.j.issn.1671-0290.2020.04.009
- VernacularTitle:A型肉毒毒素对面部伤口愈合及减少瘢痕形成的Meta分析
- Author:
Qian PENG
1
;
Xiaomei ZHAI
;
Linbo LIU
;
Lili GUO
Author Information
1. 郑州大学第一附属医院整形外科 450052；郑州大学瘢痕研究中心 450052
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2020;26(4):294-297
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the influence of botulinum toxin type A (BTXA) injections in the facial plastic surgery incision.Methods:A systematic literature search for studies which were published on PubMed, EMbase, Cochrane Central, CNKI and VIP, was performed from January 1998 to Octomber 2019. " Facial wound" , " Keloid" , " Scar" , " Cicatrix hypertrophy" , " Botulinum toxin" , " Boutulin" , " Botox" were set as the key words. We included trails related to the influence of botulinum toxin type A (BTXA) injections in the facial plastic surgery incision. The data were extracted and Rev Man 5.3 was used for meta-analysis.Results:Participants included seven randomized controlled trial of 450 patients. The Vancouver scar scale score of BTXA group was higher than those in the control group ( Z=23.92, P<0.01). The visual analogue scale score of BTXA group was higher than that of the control group ( Z=8.60, P<0.01). The scar width of BTXA group was less than that in the control group ( Z=10.84, P<0.01). Patients＇ satisfactory rate of BTXA group was higher than that of the control group ( Z=2.83, P<0.01). Conclusions:The injection treatment of BTXA for facial hyperplastic scar has certain curative effect, without obvious side effects, but the authenticity and stability of therapeutic effect have to be verified by more high quality research.
