Clinical effect of minocycline in treating severe ocularrosacea
10.3760/cma.j.issn.1671-0290.2020.04.015
- VernacularTitle:米诺环素治疗重度玫瑰痤疮眼型的临床疗效观察
- Author:
Yunfan ZHOU
1
;
Tong LIN
;
Yingnan XU
;
Qin JIANG
;
Jingsong XUE
Author Information
1. 南京医科大学附属眼科医院角膜病科 210029
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2020;26(4):318-321
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effect of minocycline on severe ocular rosacea.Methods:Twenty-three patients with severe ocular rosacea were recruited and received 8 weeks treatment. Oral minocycline 100 mg was given daily for the first 2 weeks, and 50 mg daily minocycline daily for the next 6 weeks. The best corrected visual acuity and the eye and body skin conditions before and after treatment were recorded. The visual acuity and the degree of skin and body inflammation were compared before and after treatment to evaluate the efficacy.Results:After 2 weeks of minocycline treatment for severe rosacea eye type, 14 patients had improved eye conditions and dermatitis subsided, with an effective rate of 60.87%; 23 patients had an effective rate of 100% after 8 weeks of treatment. No adverse drug reactions were seen during treatment. The visual acuity before treatment was 0.20±0.09, and the visual acuity was 0.14±0.07 8 weeks after treatment. The patients were followed up for 18 months without recurrence.Conclusions:Minocycline is safe and effective in treating severe ocular rosacea and can control recurrence.
