Effect of compound glycyrrhizin and tacrolimus ointmenta combined with photon therapy on hormone dependence facial dermatitis
10.3760/cma.j.issn.1671-0290.2020.02.017
- VernacularTitle:复方甘草酸苷与他克莫司联合红光治疗面部激素依赖性皮炎
- Author:
Zhongkui ZHANG
1
;
Sixian HE
;
Yumeng YANG
;
Guizhen ZHANG
Author Information
1. 解放军西部战区总医院皮肤科，成都 610083
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2020;26(2):135-137
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical curative effect of compound glycyrrhizin tablets and tacrolimus ointmenta combined with photon therapy on hormone dependence facial dermatitis and the safety.Methods:80 cases were randomly divided into two groups: treatment group and control group, 40 each; compound glycyrrhizin tablets and tacrolimus ointmenta were administrated to all the cases in both groups while photon therapy was added to cases in treatment group; a comparative study was made to observe the clinical effect 4 weeks after treatment between the two groups.Results:Four weeks after treatment, the effective rate was 86.67% in treatment group and 63.33% in control group, the difference was of statistical significance ( χ2=4.36, P<0.05); the total scores of symptoms and signs decreased obviously in both groups while the difference between the groups was of statistical significance ( t=3.10, P<0.05); topical medication led to drug adverse reaction in 4 cases in treatment group and 3 cases in control group with the manifestation of tolerable aggravated facial erythema and twinge while the adverse reaction disappeared gradually with the drug application keeping on for about 1 week. Conclusions:Compound glycyrrhizin tablets and tacrolimus ointmenta combined with photon therapy is of definite curative effect on hormone dependence facial dermatitis with good safety.
