Current clinical situation and challenge for liquid chromatography-tandem mass spectrometry in quantitative detection
10.3760/cma.j.cn114452-20200619-00564
- VernacularTitle:液相色谱串联质谱技术定量检测的临床应用现状与挑战
- Author:
Liqiao HAN
1
;
Qiaoxuan ZHANG
;
Xianzhang HUANG
Author Information
1. 广州中医药大学第二附属医院（广东省中医院）检验医学部，广州510120
- From:
Chinese Journal of Laboratory Medicine
2020;43(10):945-950
- CountryChina
- Language:Chinese
-
Abstract:
The performance of high sensitivity, specificity and throughput makes liquid chromatography-tandem mass spectrometry (LC-MS/MS) quickly developed and well applicated in clinical laboratories, such as quantitative detection of steroids, vitamins and metabolic small molecules, monitoring drug concertrations as well as the establishing reference methods or verifying reference materials. However, there were still some challenges for the widespread clinical application of LC-MS/MS.
