Re-positive nucleic acid detection in COVID-19 patients after discharge from hospital
10.3760/cma.j.cn114452-20200303-00170
- VernacularTitle:五例新型冠状病毒肺炎确诊患者出院后核酸检测"复阳"的病例分析
- Author:
Shenshen ZHI
1
;
Yi XU
;
Yaokai CHEN
;
Xiaorong MENG
;
Wei ZHANG
;
Qinhong ZHANG
;
Weizhi BAI
;
Yingbing ZHOU
;
Yuyao LUO
;
Lijuan LI
;
Jianda LIU
;
Wei LI
Author Information
1. 重庆市急救医疗中心检验科，重庆 400014
- From:Chinese Journal of Laboratory Medicine
2020;43(9):923-926
- CountryChina
- Language:Chinese
-
Abstract:
Cases of 2019-nCoV nucleic acid and antibody (IgM and IgG total antibody) after discharge from a hospital in Chongqing were continuously monitored. It was found that 5 cases of "re-positive" phenomenon, 5 cases of antibody were positive, and there was a trend of increasing with time. "Re-Positive" may be related to the following three factors. Children with asymptomatic infection had a long time of fecal detoxification.There were two consecutive nucleic acid tests "false negative" caused by various reasons.The virus clearance in patients was not complete, and the discharge standard was not conservative enough. The analysis of the causes of "Re-Positive" patients and the discussion of its infection will help us reveal more characteristics of this virus, and to provide a new basis for the discharge standard in the constantly updated diagnosis and treatment programme.
