The roles and mechanisms of circular RNAs in viral infectious diseases
10.3760/cma.j.cn114452-20191225-00754
- VernacularTitle:环状RNA在病毒感染性疾病中的作用机制
- Author:
Chihui LI
1
;
Ran TAO
;
Wei LI
;
Shiqiang SHANG
Author Information
1. 金华市人民医院检验科，金华 323000
- From:
Chinese Journal of Laboratory Medicine
2020;43(7):758-762
- CountryChina
- Language:Chinese
-
Abstract:
Circular RNAs (circRNAs) are covalently linked circular single-stranded RNAs, which have the characteristics like abundance,conservation, stabilization and specificity. It is demonstrated that circRNA plays an important roles in the regulation of gene expression and multiple signal pathways of diseases such as cancer, cardiovascular disease, nervous system disease and autoimmune disease. In recent years, it has been reported that circRNAs are expressed abnormally in viral infectious diseases. CircRNA is expected to be a potential biomarker for viral infectious diseases and a potential target for disease therapy. In this review we briefly introduced the research progression of the roles and mechanisms of circular RNAs in viral infectious diseases and provides the references for future study.
