Blood biomarkers for bronchial asthma
10.3760/cma.j.cn114452-20200213-00066
- VernacularTitle:支气管哮喘外周血生物标志物研究的新进展
- Author:
Yubao CUI
1
;
Zhiyong YANG
;
Xiangren A
;
Peiyan ZHENG
Author Information
1. 南京医科大学附属无锡人民医院检验科，无锡 214023
- From:
Chinese Journal of Laboratory Medicine
2020;43(5):540-546
- CountryChina
- Language:Chinese
-
Abstract:
Bronchial asthma is characterized by airway inflammation, bronchial hyperresponsiveness, and recurrent episodes of reversible airway obstruction. Due to different pathophysiological mechanisms, the disease is very heterogeneous in clinical manifestation, course of disease, response to treatment, phenotype etc. There is a strong need for biomarkers to assess the characteration and severity of the disease. Recently, lymphocyte and blood cells, antibodies, cytokines, chemokines, noncoding RNA and other protein markers have been studied as blood biomarkers of asthma. The present article summarized these biomarkers in diagnosis, phenotyping and treatment efficacy.
