Clinical application of anti-Müllerian hormone in disorders of sex development in children
10.3760/cma.j.cn114452-20191108-00650
- VernacularTitle:抗缪勒管激素在儿童性发育相关疾病中的临床应用
- Author:
Caizhi HUANG
1
;
Cong ZHANG
;
Liya MO
Author Information
1. 湖南省儿童医院检验中心，长沙 410007
- From:
Chinese Journal of Laboratory Medicine
2020;43(5):529-532
- CountryChina
- Language:Chinese
-
Abstract:
The process of sex development in children is complex and sequential. The diseases and etiologies associated with sex development are various, and laboratory indexes evaluating the diseases are scarce, which lead to the difficulty in diagnosis. Anti-Müllerian hormone(AMH) is a kind of reproductive hormone closely related to sex development. At present, AMH is widely used to evaluate ovarian reserve and to assist in the field of reproduction. AMH takes part in the process of sex development regulated by hypothalamic-pituitary-gonadal axis, and the change of AMH level may indicate the occurrence of diseases associated with sex development in children. This review will focus on the clinical application of AMH in precocious puberty, delayed puberty and disorders of sex development.
