Causes and countermeasures of false-negative results for 2019 novel coronavirus nucleic acid test
10.3760/cma.j.issn.1009-9158.2020.03.005
- VernacularTitle:新型冠状病毒核酸检测假阴性结果原因分析及对策
- Author:
Jin LI
1
;
Guangming YE
;
Liangjun CHEN
;
Jiajun WANG
;
Yirong LI
Author Information
1. 武汉大学中南医院检验科，武汉 430071
- From:
Chinese Journal of Laboratory Medicine
2020;43(3):221-225
- CountryChina
- Language:Chinese
-
Abstract:
In December 2019, a cluster of patients with pneumonia of unknown cause were linked to a seafood wholesale market in Wuhan, China. Some studies found that the virus was a new kind of virus which had never been found in the human body. Then, the virus was named 2019 novel coronavirus (2019-nCoV) by the World Health Organization (WHO). 2019-nCoV nucleic acid detection is one of the essential indicators of COVID-19. Recently, some false-negative cases in China-Japan Friendship Hospital and Hangzhou Hospital led the clinical doctors to question the value of the nucleic acid detection. In this paper, more than 3 000 results of 2019-nCoV detection in Zhongnan Hospital, Wuhan University were analyzed. Attention should be paid to the root cause of false-negative results and the related countermeasures should be taken.
