Understanding the influence factors in viral nucleic acid test of 2019 novel coronavirus
10.3760/cma.j.issn.1009-9158.2020.03.003
- VernacularTitle:正确认识新型冠状病毒核酸检测的影响因素
- Author:
Xi MO
1
;
Wei QIN
;
Qihua FU
;
Ming GUAN
Author Information
1. 国家儿童医学中心 上海交通大学医学院附属上海儿童医学中心精准医疗实验诊断中心，上海 200127
- From:
Chinese Journal of Laboratory Medicine
2020;43(3):213-216
- CountryChina
- Language:Chinese
-
Abstract:
At present, the prevention and control of new coronavirus has entered a critical period. However, the use of quantitative real-time PCR (qRT-PCR)assays for the detection of viral nucleic acid, as a crucial diagnostic approach, has been doubted in clinical practice. Herein, we have reviewed the current status of epidemic prevention and control, latest development of detection technologies, disease characteristics, clinical sampling and transport. It has also discussed the factors that may affect the performance of viral nucleic acid detection, and suggested some effective methods to improve the detection performance of the assays.
