Relationship between tumor necrosis factor-α and retinopathy of prematurity
10.3760/cma.j.cn511434-20180408-00106
- VernacularTitle:肿瘤坏死因子-α与早产儿视网膜病变的相关性研究现状及进展
- Author:
Zhenquan WU
1
;
Lei ZHENG
;
Jian ZENG
;
Guoming ZHANG
Author Information
1. 深圳市眼科医院 深圳眼科学重点实验室 暨南大学附属深圳眼科医院 518040
- From:
Chinese Journal of Ocular Fundus Diseases
2020;36(3):249-252
- CountryChina
- Language:Chinese
-
Abstract:
The exact pathophysiological mechanisms of retinopathy of prematurity (ROP) remain elusive. The risk factors of ROP include excessive oxygen therapy, malnutrition, infection and inflammation. Among the factors above, the effect of inflammation on ROP has received more attention. TNF-α is a biological active protein which is involved in neovascularization and inflammation. It may play a role in the development of ROP. This review summarized the studies on the association between TNF-α and ROP in recent years, so as to provide a new way to further study the pathogenesis and treatment methods of ROP.
