Advances in the molecular mechanism of myocardial insulin resistance
10.3760/cma.j.cn112434-20200108-00010
- VernacularTitle:心肌胰岛素抵抗及其发生机制的研究进展
- Author:
Kaiyuan CHEN
1
;
Guiyou LIANG
Author Information
1. 贵州医科大学附属医院心血管外科，贵阳 550000
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2020;36(7):442-446
- CountryChina
- Language:Chinese
-
Abstract:
Myocardial ischamic-reperfusion(MIRI) is one of the leading causes of cardiac dysfunction and even death with patient after cardiopulmonary bypass, its mechanism is complex and involved widely. Recent research has found that myocardial insulin resistance is an important mechanism of MIRI. But its mechanism has not been fully elucidated. Therefore, this paper reviews the study of myocardial insulin resistance and myocardial ischemia-reperfusion injury mechanism in recent years, to preliminarily clarify the regulatory role of insulin signal in MIRI and provide new ideas for the future research on the prevention and treatment of MIRI.
