Recent research advances in the relationship between competing endogenous RNA and lung neoplasma
10.3760/cma.j.cn112434-20190925-00333
- VernacularTitle:ceRNA网络在肺癌中的研究进展
- Author:
Liangliang CHEN
1
;
Zhimin YIN
;
Yusheng SHU
Author Information
1. 扬州大学临床医学院 江苏省苏北人民医院胸外科 225001
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2020;36(5):317-320
- CountryChina
- Language:Chinese
-
Abstract:
Non-coding RNAs can be constructed into a complex network of ceRNA by competitive combination of common microRNA recognition sequences(MREs). At present, abnormal expression of non-coding RNAs has been found in many human cancers, including lung cancer. More over, many kinds of ceRNA-microRNA-RNA have been found, which have been proved to be involved in the biological processes of lung cancer, such as occurrence, invasion, metastasis, drug resistance and prognosis. This review focuses on the differential expression of ceRNA network members in lung cancer cells and the effects of their specific changes on lung cancer.
