Establishment of gastrointestinal anastomosis by magnetic compression technique in rabbits
10.3760/cma.j.cn321463-20200526-00580
- VernacularTitle:磁压榨技术建立胃肠吻合的动物实验研究
- Author:
Yi LIN
1
;
Lin JI
;
Qian FAN
;
Senlin ZHU
;
Xingyi MOU
;
Yuwei WU
;
Yixing LI
;
Bo DENG
;
Yong ZHANG
;
Feng MA
;
Yi LYU
;
Xiaopeng YAN
Author Information
1. 西安交通大学第一附属医院肝胆外科 710061；西安交通大学第一附属医院精准外科与再生医学国家地方联合工程研究中心 710061；西安交通大学启德书院 710061
- From:
Chinese Journal of Digestive Endoscopy
2020;37(9):652-656
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the feasibility of establishing gastrointestinal anastomosis by magnetic compression technique in rabbits.Methods:Ten healthy New Zealand rabbits were selected as models for gastrointestinal anastomosis by magnetic compression technique. Daughter and parent magnets suitable for gastrointestinal anastomosis in rabbits were designed and manufactured. A daughter magnet was inserted into the stomach through the purse fistula in the lack of blood vessel area of gastric body, and was pushed into the duodenum along the intestinal tract. And then a parent magnet was inserted through the stomach fistula. The daughter and parent magnets were automatically attracted and pressed the gastric and intestinal walls after they were adjusted in the proper position. The stomach fistula was closed with purse string suture. After ischemia, necrosis, detachment of the tissues between magnets, gastrointestinal anastomosis was established, and the magnets and necrotic tissues were expelled together from the body through the digestive tract. Survival of experimental animals was observed. Anastomotic specimens were obtained one month after operation. The blasting pressure of anastomotic stoma was measured, and the healing of anastomotic stoma was observed with naked eyes.Results:According to the pre-designed operative route, 10 New Zealand rabbits all successfully completed the operation and survived one month after surgery. No complications occurred during perioperative period. The operation time was 35.80±4.71 min (range 28.00-43.00 min), and the magnet discharge time was 11.40±1.56 days (range 9.00-14.00 days). Anastomotic specimens were obtained one month after the operation. Gross observation showed that the anastomotic stoma of gastrointestinal bypass anastomosis healed well, and the surrounding tissues adhered slightly. The anastomotic bursting pressure was 103.00±7.95 mmHg (range 94.00-113.00 mmHg) (1 mmHg=0.133 kPa).Conclusion:The establishment of gastrointestinal anastomosis by magnetic compression technique in rabbits is simple and effective.
