Comparison of anti-reflux mucosectomy and endoscopic cardial constriction ligation on treatment of gastroesophageal reflux disease
10.3760/cma.j.cn321463-20191226-00694
- VernacularTitle:内镜下抗反流黏膜切除术和贲门缩窄术治疗胃食管反流病的临床疗效对比
- Author:
Dezhi HE
1
;
Yanyan ZHENG
;
Xiaotong WANG
;
Bingrong LIU
;
Jiansheng LI
;
Yanmiao HAN
;
Haili XU
;
Yang CHEN
;
Lijuan SONG
;
Laifu YUE
Author Information
1. 郑州大学第一附属医院消化内科 450052
- From:
Chinese Journal of Digestive Endoscopy
2020;37(8):553-557
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical efficacy of anti-reflux mucosectomy (ARMS) and endoscopic cardial constriction ligation (ECCL) on treatment of gastroesophageal reflux disease.Methods:A retrospective study was conducted on the data of 48 consecutive patients with gastroesophageal reflux disease, who underwent ARMS or ECCL at the First Affiliated Hospital of Zhengzhou University from December 2015 to August 2018. Twenty cases were in the ARMS group and 28 cases in the ECCL group. The short-term and long-term efficacies were compared between the two groups.Results:The success rate of operation was 100.0% in the both groups. The operation time of the ECCL group was significantly shorter than that of the ARMS group (8.43±1.59 min VS 34.05±12.35 min, t=-9.227, P<0.001). After 2 months follow-up, the symptom improvement rate of the ECCL group and the ARMS group was 89.3% (25/28) and 60.0% (12/20), respectively ( χ2=4.128, P=0.042). The GERD Q score of the ECCL group was significantly lower than that of the ARMS group (6.24 ±1.22 VS 7.35±1.79, t=-2.400, P=0.023). One year after operation, there were no significant differences in the symptom improvement rate, GERD Q score, DeMeester score and the time percentage of pH<4 between the two groups ( P>0.05). Conclusion:The long-term clinical effect of ARMS and ECCL is similar, but the short-term clinical effect of ECCL is superior to ARMS.
