Endoscopic ultrasound-guided iodine-125 seed implantation for treatment of dysphagia in patients with advanced esophageal cancer: a primary study
10.3760/cma.j.cn321463-20191014-00689
- VernacularTitle:内镜超声引导下碘125粒子植入术治疗晚期食管癌患者吞咽困难初探
- Author:
Chenhuan WANG
1
;
Xiangdong WANG
;
Fang LIU
;
Zikai WANG
;
Wen LI
Author Information
1. 解放军总医院第一医学中心消化科，北京 100853
- From:
Chinese Journal of Digestive Endoscopy
2020;37(5):317-320
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the safety and efficacy of endoscopic ultrasound (EUS)-guided iodine-125 seed implantation to treat dysphagia in patients with advanced esophageal cancer.Methods:Data of 4 patients with dysphagia of advanced esophageal cancer who received EUS-guided iodine-125 seed implantation in Chinese PLA General Hospital between December 2017 and November 2018 were collected in the retrospective study. The evaluation contents included technical success rate of seed implantation, complication, dysphagia grade, tumor size and other follow-up results.Results:Four patients successfully completed EUS-guided iodine-125 seed implantation. No haemorrhage, chest pain, fever, cough or other postoperative complications were reported. Three months after treatment, dysphagia grade reduced from Ⅱ-Ⅳ to 0-Ⅰ, and the tumor size in all patients showed a decrease. After 12-23 months of follow-up, 3 patients were alive, and 1 died due to advance of the cancer.Conclusion:EUS-guided iodine-125 seed implantation is a safe and effective palliative treatment method for dysphagia in patients with advanced esophageal cancer.
