Application of Q self-traction method in endoscopic submucosal dissection to the treatment of large early esophageal cancer (with video)
10.3760/cma.j.cn321463-20190906-00614
- VernacularTitle:Q法自牵引技术在大范围早期食管癌内镜黏膜下剥离术中的应用研究(含视频)
- Author:
Zhilong CHEN
1
;
Xiaolu LIN
;
Wanyin DENG
;
Jinhui ZHENG
;
Xianbin GUO
;
Guowei WANG
;
Haining LIN
;
Wei LIANG
Author Information
1. 福建医科大学省立临床医学院，福州 350001
- From:
Chinese Journal of Digestive Endoscopy
2020;37(3):163-168
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To preliminarily study the effect of Q self-traction endoscopic submucosal dissection (Q-ESD) on treatment of large early esophageal cancer (EEC).Methods:A retrospective analysis was performed on the data of 82 cases of large EEC (single lesion>1/2 cross-section diameter or longitudinal diameter length >5 cm) who underwent ESD on Fujian Provincial Hospital between January 2015 and December 2018. According to the treatment schedule, patients were divided into the conventional ESD group (n=44) and the Q-ESD group (n=38). The procedural area, time, and speed, en bloc resection rate, complete resection rate and complications of the two groups were analyzed.Results:All of the 82 lesions were resected completely under endoscope. There was no statistical difference in the procedural area [779.8 (329.9-2 552.5)mm 2 VS 875.7 (417.8-1 914.8)mm 2, U=155, P=0.636], procedural time [63 (41-177)min VS 59 (42-169)min, U=171, P=0.167] and complete resection rate [94.7% (36/38) VS 93.2% (41/44), χ2=0.086, P=0.769] between the Q-ESD group and the conventional ESD group. Compared with the conventional ESD group, the Q-ESD group had a faster dissection speed [14.9 (5.4-20.8) mm 2/min VS 9.0 (5.0-19.5) mm 2/min, U=142, P=0.035], lower muscularis propria injury rate [7.9% (3/38) VS 27.3% (12/44), χ2=5.123, P=0.023], and a lower stricture rate [5.3% (2/38) VS 20.5% (9/44), χ2=4.051, P=0.044]. No other adverse events occurred except for one case of perforation in the conventional ESD group. Conclusion:The new traction technique of Q-ESD is a safe and effective treatment for large EEC.
