Mechanism of atopic march based on intestinal microecology
10.3760/cma.j.cn112309-20191111-00374
- VernacularTitle:基于肠道微生态的特应性进程机制探讨
- Author:
Minye QU
1
;
Wenhua TAO
Author Information
1. 江苏大学附属医院中医科，国家级临床重点专科，镇江 212000
- From:
Chinese Journal of Microbiology and Immunology
2020;40(10):807-812
- CountryChina
- Language:Chinese
-
Abstract:
Allergy-related diseases are common and frequently-occurring in children. Its onset follows the sensitization transfer rule from skin allergy to respiratory allergy, which is called the natural process of allergic disease or atopic march. The relationship between intestinal microbiota and allergic diseases has been a hot topic in recent years. Immunoregulation and neuromodulation with the participation of intestinal microbiota are two important aspects that affect the development of allergic diseases. Therefore, in this paper, we systematically reviewed the interaction of bacteria-immune-neural network in atopic march from the perspective of multi-system sensitization, so as to open up new perspectives for the mechanism research and prevention of sensitization progress.
