The role of macrophages in acute pancreatitis
10.3760/cma.j.cn112309-20191013-00326
- VernacularTitle:巨噬细胞在急性胰腺炎中的作用研究进展
- Author:
Su YAN
1
;
Yupu HONG
;
Weixing WANG
Author Information
1. 武汉大学人民医院普通外科，消化系统疾病湖北省重点实验室 430060
- From:
Chinese Journal of Microbiology and Immunology
2020;40(9):720-726
- CountryChina
- Language:Chinese
-
Abstract:
Acute pancreatitis (AP) is a common and severe disease causing multiple organ dysfunction. With the deepening of research on AP pathogenesis, it has been found that macrophages play an important role in the initiation and progress of AP. The systemic innate macrophage populations, such as the pancreatic macrophages, Kupffer cells, peritoneal macrophages and pulmonary macrophages, can be activated by inflammatory mediators in different stages of pancreatitis, triggering inflammatory cascade reaction and systemic inflammatory response syndrome. This review focused on the recent progress in the role of macrophages in AP.
