Immune microenvironment in alcoholic liver disease and advances in targeted therapy
10.3760/cma.j.cn112309-20191023-00339
- VernacularTitle:酒精性肝病的免疫微环境及其靶向药物的研究进展
- Author:
Yuzi LI
1
;
Ying WANG
Author Information
1. 北京大学人民医院风湿免疫科 100044
- From:
Chinese Journal of Microbiology and Immunology
2020;40(8):640-646
- CountryChina
- Language:Chinese
-
Abstract:
Alcoholic liver disease is a common chronic liver disease. Inflammatory pathways in the immune microenvironment of the liver play important roles in the development and progression of alcoholic liver disease, providing potential targets for therapeutic interventions. This review focused on the pathophysiology of alcoholic liver disease, changes in the immune microenvironment including immune cells and inflammatory mediators, and advances in targeted therapy.