Detection of 2019-nCoV nucleic acid in different specimens from confirmed COVID-19 cases during hospitalization and after discharge
10.3760/cma.j.cn112309-20200524-00274
- VernacularTitle:新型冠状病毒肺炎住院和出院后不同标本中病毒核酸的检测
- Author:
Zerun XUE
1
;
Haifei YOU
;
Yang LUAN
;
Hailong CHEN
;
Quanli DU
;
Yuewen HAN
;
Ningxiu FAN
;
Yujie YANG
;
Yangni DENG
;
Kaixin LI
;
Liyun DANG
;
Chaofeng MA
;
Rui WU
Author Information
1. 西安市疾病预防控制中心病毒科 710054
- From:
Chinese Journal of Microbiology and Immunology
2020;40(8):569-573
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the positive rates of 2019-nCoV nucleic acid in different specimens from confirmed COVID-19 cases during hospitalization and after discharge.Methods:Patients with confirmed COVID-19 were enrolled from designated hospitals. Nasal swabs, throat swabs, and specimens of stool, urine and blood were collected during hospitalization. After the patients were discharged, nasal swabs, throat swabs and stool specimens were collected during follow-up. Real-time RT-PCR was used to detect 2019-nCoV nucleic acid.Results:This study involved 25 confirmed COVID-19 cases. During hospitalization, all patients tested positive in both nasal and throat swab 2019-nCoV nucleic acid tests, and nine of them (36.00%) were positive in stool specimen test. Urine and blood specimen test results were all negative. Nasal swabs, throat swabs and stool specimens were collected from each patient 7 d and 14 d after discharge. Two patients (8.00%) tested positive for 2019-nCoV nucleic acid again in nasal and throat swab tests on 7 d, while all stool specimen tests were negative. No 2019-nCoV nucleic acid was detected in nasal swabs, throat swabs or stool samples on 14 d.Conclusions:2019-nCoV nucleic acid was detected in stool samples of confirmed COVID-19 cases during hospitalization. Nasal and throat swab nucleic acid tests turned positive again in some patients after discharge.
