Progress in the role of leptin in immune response
10.3760/cma.j.cn112309-20190719-00219
- VernacularTitle:瘦素与免疫应答研究进展
- Author:
Mao LI
1
;
Simin WEN
;
Shuyi ZHONG
;
Huanle LUO
;
Yuelong SHU
Author Information
1. 中山大学公共卫生学院(深圳) 510006
- From:
Chinese Journal of Microbiology and Immunology
2020;40(5):387-392
- CountryChina
- Language:Chinese
-
Abstract:
Leptin, a peptide hormone discovered in the 1990s, arouses interest as it can regulate the body′s metabolism. In recent years, many studies have shown that leptin can promote the proliferation, activation and cytokine synthesis of various immune cells, and participate in innate and adaptive immune responses. This article reviewed the role of leptin and involved signaling pathways in immune response and the potential of leptin as a vaccine adjuvant.