Progress in autophagy-regulated immune cell differentiation
10.3760/cma.j.cn112309-20190727-00230
- VernacularTitle:细胞自噬调节免疫细胞分化的研究进展
- Author:
Junyao ZHU
1
;
Yongzhen ZHAI
Author Information
1. 中国医科大学附属盛京医院感染科，沈阳 110022
- From:
Chinese Journal of Microbiology and Immunology
2020;40(4):305-310
- CountryChina
- Language:Chinese
-
Abstract:
As a conservative lysosomal degradation pathway, autophagy possess various functions that have been well studied in the immune system. Regulatory effects of autophagy on the differentiation of immune cells have been gradually revealed. In order to investigate the specific mechanisms, it is very necessary to summarize the role of autophagy in the proliferation, development and differentiation of immune cells. Effects of autophagy on the functions and differentiation of immune cells have been summarized by introducing the selective degradation function of autophagy in some articles. This review focused on some classical immune cells and elucidated the important regulatory effects of autophagy and the nutrient signaling metabolic pathways involved in autophagy on immune cell differentiation.
