Progress in association between high mobility group protein box 1 (HMGB1) and immune imbalance in primary Sj?gren′s syndrome
10.3760/cma.j.cn112309-20190908-00293
- VernacularTitle:原发性干燥综合征中高迁移率族蛋白1与免疫失衡的研究进展
- Author:
Xue LI
1
;
Ziqi HOU
;
Shenghua LI
;
Shufen LIANG
Author Information
1. 山西医科大学第二临床医学院，太原 030001
- From:
Chinese Journal of Microbiology and Immunology
2020;40(4):311-315
- CountryChina
- Language:Chinese
-
Abstract:
Primary Sj?gren′s syndrome (pSS) is a relatively common autoimmune systemic disease. The pathogenesis of pSS has not been fully elucidated. With the deepening of research, it is found that high mobility group protein box 1 (HMGB1) is associated with the pathogenesis of pSS, and immunomodulatory abnormalities have become a research hotspot. This article reviewed the association between HMGB1 and immune imbalance in the pathogenesis of pSS.
