Intrahepatic cholestasis of pregnancy and fetal cardiac damage
10.3760/cma.j.cn113903-20190629-00413
- VernacularTitle:妊娠期肝内胆汁淤积症与胎儿心脏损害
- Author:
Taojun DU
1
;
Yong ZHANG
;
Jinlin WU
Author Information
1. 四川大学华西第二医院新生儿科，成都 610041
- From:
Chinese Journal of Perinatal Medicine
2020;23(5):354-357
- CountryChina
- Language:Chinese
-
Abstract:
The risk of intrauterine death increases significantly in women with severe intrahepatic cholestasis of pregnancy. Fetal cardiac factors are considered to be possible important causes. However, the mechanisms of intrahepatic cholestasis of pregnancy causing fetal cardiac damage are still unclear. The possible mechanisms focus on the theories of acute hypoxia of the placenta and the toxic effects of bile acids. In this paper we summarize the studies on fetal heart damage caused by intrahepatic cholestasis of pregnancy, with a view to raising awareness of this disease.
