Prevalence and determinants of masked hypertension defined by home blood pressure monitoring in peritoneal dialysis patients
10.3760/cma.j.cn441217-20200302-00120
- VernacularTitle:腹膜透析患者家庭血压监测定义的隐蔽性高血压的患病率及危险因素分析
- Author:
Tong LIN
1
;
Xi XIA
;
Rui YANG
;
Jing YU
;
Yagui QIU
;
Jianxiong LIN
;
Chunyan YI
;
Haiping MAO
;
Xiao YANG
;
Fengxian HUANG
Author Information
1. 中山大学附属第一医院肾内科，广州 510080；卫健委和广东省重点实验室，广州 510080
- From:
Chinese Journal of Nephrology
2020;36(9):666-674
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the prevalence of masked hypertension defined by home blood pressure monitoring in patients on peritoneal dialysis (PD) and examine its determinants.Methods:The patients who performed PD in the First Affiliated Hospital of Sun Yat-sen University from January 1, 2006 to December 31, 2013 were recruited. Baseline demographic, clinical and biochemical examination data were collected to analyze the prevalence and clinical characteristics in patients with masked hypertension defined by home blood pressure monitoring. Multivariate logistic regression model was used to analyze the related risk factors of masked hypertension in PD patients with clinic normotension.Results:There were 1 425 patients (866 males) enrolled in this study, with age of (46.9±14.9) years and body mass index of (21.6±3.1) kg/m 2. The prevalence of masked hypertension in PD patients was 31.9%, and the prevalence of masked hypertension in patients with clinic normotension was 57.5%. Multivariate logistic regression analysis showed that higher body mass index ( OR=1.057, 95% CI 1.001-1.116, P=0.047), incorporating diabetes mellitus ( OR=1.996, 95% CI 1.160-3.433, P=0.013), use of multiple antihypertensive drugs ( OR=1.336, 95% CI 1.122-1.590, P=0.001) and elevated office blood pressure ( OR=1.785, 95% CI 1.546-2.060, P<0.001) were independent risk factors of masked hypertension in PD patients with clinic normotension. Conclusions:The prevalence of masked hypertension is high in PD patients. Higher body mass index, incorporating diabetes mellitus, use of multiple antihypertensive drugs and elevated office blood pressure are independent risk factors for masked hypertension in PD patients with clinic normotension.
