Imaging and pathological study of primary central nervous system lymphoma in special sites
10.3760/cma.j.cn113694-20191215-00783
- VernacularTitle:特殊部位原发性中枢神经系统淋巴瘤影像学及病理研究
- Author:
Yanfan CHEN
1
;
Qiande QIU
;
Hai WU
;
Xuming LIU
;
Mengmeng WU
;
Zhihan YAN
Author Information
1. 温州医科大学温州市第三临床学院，温州市人民医院放射科 325000
- From:
Chinese Journal of Neurology
2020;53(9):700-705
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the imaging and pathological features of primary central nervous system lymphoma in special sites, and analyze some misdiagnosed cases to provide help for clinical diagnosis.Methods:Thirty-nine patients with primary central nervous system lymphoma diagnosed by pathology from 2000 to 2019 in Wenzhou People′s Hospital and the Second Affiliated Hospital of Wenzhou Medical University were retrospectively analyzed. The imaging and pathological features of primary central nervous system lymphoma in special sites were summarized, and the misdiagnosed cases in these special sites were analyzed.Results:Primary central nervous system lymphoma in special sites included one case of primary dural lymphoma, with thickening of dura mater and obvious enhancement; two cases with lesions in lateral ventricle, with homogeneous enhancement, involving ependyma and spreading to medulla oblongata; two cases with lesions in middle cerebellar peduncle, with patchy abnormal signals and no specific masses, mild to moderate enhancement after enhancement, and one misdiagnosed as demyelinating lesions; one case with lesions in the sellar region which obviously enhanced with a typical “dent sign”, misdiagnosed as invasive pituitary tumor. All the pathological findings indicated diffuse large B cell lymphoma.Conclusions:It is difficult to diagnose primary central nervous system lymphoma in special sites, which is easy to cause misdiagnosis. Understanding its imaging characteristics and pathology can help to diagnose the disease.
