The research progress on silent mating type information regulation 2 homolog-3 and neurodegenerative diseases
10.3760/cma.j.cn113694-20191104-00682
- VernacularTitle:沉默信息调节因子2相关酶类3与神经系统变性病的研究进展
- Author:
Huilin LIU
1
;
Xiaofan XUE
;
Lichun ZHOU
Author Information
1. 首都医科大学附属北京朝阳医院神经内科100043
- From:
Chinese Journal of Neurology
2020;53(8):627-630
- CountryChina
- Language:Chinese
-
Abstract:
Silent mating type information regulation 2 homolog-3(Sirt3) has a close relationship with neurodegenerative diseases. As researches developing, more and more abnormal proteins have been found depositted in neuron, and these abnormal proteins could induce mitochondrion oxidative stress injury. But Sirt3 could resist abnormal protein′s oxidative stress injury by deacetylation. So Sirt3 may delay the progression of neurodegenerative diseases.
